Lower levels of high-density lipoprotein cholesterol in urban Africans presenting with communicable versus non-communicable forms of heart disease: the ‘Heart of Soweto’ hospital registry study

  • August 07, 2014 | Jasmine G Lyons,1,2 Karen Sliwa,3,4 Melinda J Carrington,1,4,5 Frederick Raal,6 Sandra Pretorius,3 Friedrich Thienemann,3,7,8 S | Category: HEDUAfrica news

Photo courtesy of Ravindra Gandhi

An investigation into whether urban Africans displayed lower levels of atheroprotective high-density lipoprotein cholesterol (HDLC) when presenting with communicable versus non-communicable forms of heart disease (HD) as both acute infection and chronic inflammation reduce HDLC levels.

Heart diseases (HDs) with infectious aetiology have long been the principal forms of cardiovascular disease (CVD) in sub-Saharan Africa. However, epidemiological transition has seen increased prevalence of non-communicable forms of HD in these populations.

This phenomenon is largely driven by complex, population-wide changes in demographic, social and economic status, with associated changes in lifestyle habits.